Study on suitable analysis method for HIV-1 non-catalytic integrase inhibitor.
Ki Hoon ParkMinjee KimSeoung Eun BaeHee Jung LeeKyung-Chang KimByeong Sun ChoiYoung Bong KimPublished in: Virology journal (2021)
Accordingly, we recommend application of other assay procedures, such as p24 ELISA or reverse transcription activity, in lieu of the TZM-bl luciferase system for preliminary NCINI drug screening. Utilization of appropriate analytical methods based on underlying mechanisms is necessary for accurate assessment of drug efficacy.