Therapeutic Actionability of Circulating Cell-Free DNA Alterations in Carcinoma of Unknown Primary.
Shumei KatoCaroline WeipertSophia GumasRyosuke OkamuraSuzanna LeeJason K SicklickJennifer SaamRazelle KurzrockPublished in: JCO precision oncology (2021)
In summary, cfDNA frequently reveals strong level-of-evidence actionable alterations in CUP, and high degrees of matching to therapy correlates with better outcomes.