Paclitaxel Has a Reduced Toxicity Profile in Healthy Rats After Polymeric Micellar Nanoparticle Delivery.

Jun LuYuqing LouYanwei ZhangRunbo ZhongWei ZhangXueyan ZhangHuimin WangTianqing ChuBaohui HanHua Zhong

Published in: International journal of nanomedicine (2023)

This study introduces the toxicological profile of the engineered nanoparticle Pm-Pac and provides a novel perspective on the Pm-Pac-induced histopathological-toxicological profile in a rat model.

Keyphrases

particulate matter
air pollution
heavy metals
drug delivery
polycyclic aromatic hydrocarbons
oxidative stress
high glucose
diabetic rats
oxide nanoparticles
drug release