In vitro characterization of MOD-5014, a novel long-acting carboxy-terminal peptide (CTP)-modified activated FVII.

A Bar-IlanTami LivnatM HoffmannL BinderM ZakarR GuyY FelikmanL MoschcovichB ShenkmanDougald M MonroeO HershkovitzG KenetG Hart

Published in: Haemophilia : the official journal of the World Federation of Hemophilia (2018)

The comparable in vitro activity of MOD-5014 and rhFVIIa paves the way for in vivo pharmacology evaluations of MOD-5014 in preparation for clinical studies.

Keyphrases

mass spectrometry
high resolution