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Multimodal Imaging of Substantia Nigra in Parkinson's Disease with Levodopa-Induced Dyskinesia.

Dongning SuYawen GanZhe ZhangYusha CuiZhijin ZhangZhu LiuZhan WangJunhong ZhouVesna SossiA Jon StoesslTao WuJing JingTao Feng
Published in: Movement disorders : official journal of the Movement Disorder Society (2023)
Our multimodal imaging findings highlight greater neurodegeneration in SN and the altered nigrostriatal connectivity in PD-LID. These characteristics provide a new perspective into the role of SN in the pathophysiological mechanisms underlying PD-LID. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Keyphrases
  • high resolution
  • pain management
  • parkinson disease
  • diabetic rats
  • high glucose
  • resting state
  • functional connectivity
  • deep brain stimulation
  • systematic review
  • white matter
  • mass spectrometry
  • oxidative stress