White Matter Disruption in Pediatric Traumatic Brain Injury: Results from ENIGMA Pediatric Moderate to Severe Traumatic Brain Injury.
Emily Larson DennisKaren CaeyenberghsKristen R HoskinsonTricia L MerkleyStacy J SuskauerRobert F AsarnowTalin BabikianBrenda L Bartnik-OlsonKevin BickartErin D BiglerLinda Ewing-CobbsAnthony A FigajiChristopher C GizaNaomi J Goodrich-HunsakerCooper B HodgesElizabeth S Hovenden AaAndrei IrimiaMarsh KönigsHarvey S LevinHannah M LindseyJeffrey E MaxMary R NewsomeAlexander OlsenNicholas P RyanAdam T SchmidtMatthew S SpruiellBenjamin Sc WadeAshley L WareChristopher G WatsonAnne L WheelerKeith Owen YeatesBrandon A ZielinskiPeter V KochunovNeda JahanshadPaul M ThompsonDavid F TateElisabeth A WildePublished in: Neurology (2021)
WM disruption after msTBI is widespread, persistent, and influenced by demographic and clinical variables. Future work will test techniques for harmonizing neurocognitive data, enabling more advanced analyses to identify symptom clusters and clinically-meaningful patient subtypes.