The Natural History of Medial Meniscal Tears in the ACL Deficient and ACL Reconstructed Rat Knee.

Akinori KaneguchiJunya OzawaKengo MinamimotoKaoru Yamaoka

Published in: Cartilage (2021)

Our results suggest that ACLT-induced joint laxity induces secondary medial meniscal tears through meniscal proliferation and ossicle formation via endochondral ossification. Joint re-stabilization by ACLR suppresses meniscal proliferation and ossicle formation and consequently prevents secondary meniscal tears.

Keyphrases

anterior cruciate ligament reconstruction
anterior cruciate ligament
rotator cuff
signaling pathway
high glucose
total knee arthroplasty
diabetic rats
drug induced
knee osteoarthritis