Mapping hippocampal and thalamic atrophy in epilepsy: A 7-T magnetic resonance imaging study.
Alfredo LucasSofia MouchtarisAshley TranquilleNishant SinhaRyan GallagherMarissa MojenaJoel M SteinSandhitsu DasKathryn A DavisPublished in: Epilepsia (2024)
Leveraging 7-T MRI, we demonstrate widespread hippocampal and thalamic atrophy in epilepsy. Through unsupervised machine learning, we demonstrate patterns of volumetric atrophy that vary depending on disease subtype. Incorporating these atrophy patterns into clinical practice could help better stratify patients to surgical treatments and specific device implantation strategies.
Keyphrases
- machine learning
- magnetic resonance imaging
- end stage renal disease
- clinical practice
- newly diagnosed
- temporal lobe epilepsy
- contrast enhanced
- ejection fraction
- deep brain stimulation
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- artificial intelligence
- magnetic resonance
- patient reported outcomes
- mass spectrometry
- patient reported