The ACE2/Ang-(1-7)/MasR axis alleviates brain injury after cardiopulmonary resuscitation in rabbits by activating PI3K/Akt signaling.

Jing ChengHong YangFang ChenLi QiuFang ChenYanhua DuXiangping Meng

Published in: Translational neuroscience (2024)

Collectively, the ACE2/Ang-(1-7)/MasR axis alleviates CA/CPR-induced brain injury through attenuating hippocampal neuronal apoptosis by activating PI3K/Akt signaling.

Keyphrases

brain injury
pi k akt
signaling pathway
cardiopulmonary resuscitation
cell cycle arrest
cardiac arrest
angiotensin ii
cerebral ischemia
subarachnoid hemorrhage
angiotensin converting enzyme
cell proliferation
cell death
mouse model
diabetic rats
high glucose
drug induced
endothelial cells
protein kinase