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Opicapone for the treatment of early wearing-off in levodopa-treated Parkinson's disease: pooled analysis of patient level data from two randomized open-label studies.

Joaquim José FerreiraJee-Young LeeHyeo-Il MaBeomseok JeonWerner PoeweAngelo AntoniniFabrizio StocchiDaniela M RodriguesMiguel M FonsecaGuillermo Castilla-FernándezJoerg HolenzJosé-Francisco RochaOlivier Rascolnull null
Published in: Journal of neurology (2024)
In these short-term trials, introducing adjunct opicapone was more effective at reducing OFF time than adding another 100 mg levodopa dose in PD patients with early signs of wearing-off.
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