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The B7-H3-Targeting Antibody-Drug Conjugate m276-SL-PBD Is Potently Effective Against Pediatric Cancer Preclinical Solid Tumor Models.

Nathan M KendserskyJarrett LindsayE Anders KolbMalcolm A SmithBeverly A TeicherStephen W EricksonEric Jay EarleyYael P MosseDaniel MartinezJennifer PogorilerKateryna KrytskaKhushbu PatelDavid GroffMatthew TsangSamson GhiluYifei WangSteven SeamanYang FengBrad St CroixRichard G GorlickRaushan T KurmashevaPeter J HoughtonJohn M Maris
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
m276-SL-PBD has significant antitumor activity across a broad panel of pediatric solid tumor PDX models.
Keyphrases
  • cancer therapy
  • papillary thyroid
  • childhood cancer
  • squamous cell
  • squamous cell carcinoma
  • stem cells
  • cell therapy
  • young adults
  • bone marrow