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Antibacterial and antibiotic-potentiation activity of the constituents from aerial part of Donella welwitshii (Sapotaceae) against multidrug resistant phenotypes.

Michel-Gael F GuefackMarcelle O NgangoueArmelle T MbavengPaul NayimJenifer R N KueteCarine M N NgaffoGodloves F ChiBathelemy NgameniBonaventure T NgadjuiVictor Kuete
Published in: BMC complementary medicine and therapies (2022)
The overall results of the current work demonstrate that diospyric acid (7), 28-hydroxy-β-amyrin (8) and oleanolic acid (9) are the major bioactive constituents of Donella welwitschia towards Gram-negative bacteria expressing MDR phenotypes.
Keyphrases
  • multidrug resistant
  • drug resistant
  • essential oil
  • gram negative
  • acinetobacter baumannii
  • escherichia coli
  • silver nanoparticles
  • wound healing