The biochemical pattern defines MASLD phenotypes linked to distinct histology and prognosis.
Javier AmpueroRocío AllerRocío Gallego-DuránJavier CrespoJose Luis CallejaCarmelo García-MonzónJudith Gómez-CamareroJoan CaballeríaOreste Lo IaconoLuis IbañezJavier García-SamaniegoAgustín AlbillosRubén FrancésConrado Fernández-RodríguezDouglas Maya-MilesMoisés DiagoMaria PocaRaúl J AndradeRaquel LatorreFrancisco JorqueraRosa María MorillasDesamparados EscuderoManuel Hernández-GuerraMaría Jesús Pareja-MegiaJesús M BanalesPatricia AspichuetaSalvador BenllochJosé Miguel RosalesJuan TurnesManuel Romero-Gómeznull nullPublished in: Journal of gastroenterology (2024)
The H-pattern exhibited greater necro-inflammation in the histology than the C-pattern, whereas the latter showed more cirrhosis. The accuracy of NITs in detecting fibrosis was decreased in H-pattern. The occurrence of decompensated events and mortality was predominant in C-pattern. Therefore, identifying MASLD phenotypes based on the biochemical presentation could be relevant for clinical practice.