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Low-Dose Planned Glucarpidase Allows Safe Outpatient High-Dose Methotrexate Treatment for CNS Lymphoma.

Lauren R SchaffDean CarlowRyan SchofieldVenissala WongchaiJuli MadzsarAllison HydeAnne S ReinerKatherine S PanageasLisa M DeAngelisIngo K MellinghoffMina LobbousLouis Burt NaborsChristian Grommes
Published in: JCO oncology practice (2024)
Outpatient HD-MTX with glucarpidase is safe and well-tolerated and has the potential to alter standard treatment for CNS lymphoma.
Keyphrases
  • high dose
  • low dose
  • diffuse large b cell lymphoma
  • blood brain barrier
  • stem cell transplantation
  • risk assessment
  • human health