Diffuse optical tomography breast imaging measurements are modifiable with pre-surgical targeted and endocrine therapies among women with early stage breast cancer.

Julia E McGuinnessMirella L AltoeAlessandro MaroneLauren E FranksShing M LeeHyun K KimMariella TejadaMeghna S TrivediMelissa K AccordinoKatherine D CrewDawn L HershmanAndreas H HielscherKevin Kalinsky

Published in: Breast cancer research and treatment (2021)

We demonstrated that DOTBIS-derived measurements are modifiable with pre-surgical AKT inhibition and endocrine therapy, supporting further investigation of DOTBIS as a potential imaging assessment of response to neoadjuvant targeted therapies in early stage breast cancer.

Keyphrases

early stage
high resolution
rectal cancer
sentinel lymph node
signaling pathway
cell proliferation
lymph node
squamous cell carcinoma
locally advanced
mesenchymal stem cells
breast cancer risk
photodynamic therapy
cell therapy
human health