Oxidative Stress in Obstructive Sleep Apnea Syndrome: Putative Pathways to Hearing System Impairment.

Pierluigi MastinoDavide RosatiGiulia de SoccioMartina RomeoDaniele PentangeloStefano VenarubeaMarco FiorePiero Giuseppe MelianteCarla Petrella Christian BarbatoAntonio Minni

Published in: Antioxidants (Basel, Switzerland) (2023)

Untreated OSAS affects the hearing system at multiple levels. Oxidative stress due to intermittent hypoxia is the main pathogenetic mechanism of damage. CPAP has no effects (positive or negative) on hearing function. More studies are needed, with the evaluation of extended high frequencies, the execution of vocal audiometry in noisy environments, and the evaluation of potential biomarkers due to oxidative stress.

Keyphrases

oxidative stress
obstructive sleep apnea
dna damage
hearing loss
ischemia reperfusion injury
diabetic rats
induced apoptosis
positive airway pressure
endothelial cells
heat shock
case control