Mycobacterium dormancy and antibiotic tolerance within the retinal pigment epithelium of ocular tuberculosis.

Rachel LiuJoshua N DangRhoeun LeeJae Jin LeeNiranjana KesavamoorthyHossein AmeriNarsing RaoHyungjin Eoh

Published in: bioRxiv : the preprint server for biology (2024)

within RPE cells can be restored by a metabolic manipulation strategy such as co-treatment of antibiotic with the most downstream glycolysis metabolite, phosphoenolpyruvate.

Keyphrases

mycobacterium tuberculosis
induced apoptosis
cell cycle arrest
pulmonary tuberculosis
oxidative stress
endoplasmic reticulum stress
combination therapy
cell proliferation
replacement therapy
smoking cessation