Electric signals counterbalanced posterior vs anterior PTEN signaling in directed migration of Dictyostelium.

Bing SongYu GuWenkai JiangYing LiWayne Nishio AyreZhipeng LiuTao YinChristopher JanetopoulosMiho IijimaPeter DevreotesMin Zhao

Published in: Cell & bioscience (2021)

PTEN controls electrotaxis by coordinately regulating asymmetric redistribution of myosin to the posterior, and PIP3/F-actin to the anterior region of the directed migration cells.

Keyphrases

pi k akt
cell cycle arrest
induced apoptosis
cell proliferation
signaling pathway
binding protein
endoplasmic reticulum stress