Considerations Using Harmaline for a Primate Model of Tremor.
Edward M BelloMadeline BlumenfeldJoan DaoJordan D S KriegLucius K WilmerdingMatthew D JohnsonPublished in: Tremor and other hyperkinetic movements (New York, N.Y.) (2021)
The harmaline-primate is revisited for its potential as a preclinical model of tremor. Spontaneous tremor was heterogenous in amplitude across subjects despite similar harmaline doses, action tremors were not consistently observed, and performance on a behavioral task degraded with higher dosages.