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YBX1 promotes stemness and cisplatin insensitivity in intrahepatic cholangiocarcinoma via the AKT/β-catenin axis.

Xiaodong ShiZhiliang HuShilei BaiChen ZongHui XueYao LiFengwei LiLiangrui ChenJianbing XuanYong XiaLixin WeiFeng ShenKui Wang
Published in: The journal of gene medicine (2024)
YBX1 is upregulated in ICC and promotes stemness and cisplatin insensitivity via the AKT/β-catenin axis. Our study describes a novel potential therapeutic target for improving ICC prognosis.
Keyphrases
  • epithelial mesenchymal transition
  • cell proliferation
  • signaling pathway
  • stem cells
  • cancer stem cells
  • risk assessment