Role of the extent of prophylactic regional lymph node radiotherapy on survival in high-risk neuroblastoma: A report from the COG A3973 study.
Steve E BraunsteinWendy B LondonSusan G KreissmanJudith G VillablancaAndrew M DavidoffKenneth DeSantesRobert P CastleberryKevin MurrayLisa DillerKatherine K MatthaySusan L CohnBarry L ShulkinDaniel von AllmenMarguerite T ParisiCollin Van RynJulie R ParkMichael P La QuagliaDaphne A Haas-KoganPublished in: Pediatric blood & cancer (2019)
Although local control remains a significant component of treatment of high-risk neuroblastoma, our results suggest there is no benefit of extensive lymph node irradiation, irrespective of the extent of surgical resection preceding stem cell transplant.