Covalent Organic Framework (COF): A Drug and Carrier to Attenuate Retinal Ganglion Cells Death in an Acute Glaucoma Mouse Model.

Ke YaoXin LiangGuiyang ZhangYan RongQiuxiang ZhangQiaobo LiaoHong ZhangKai XiJunming Wang

Published in: Polymers (2022)

COF may act as both an RGC protection agent and a carrier for prolonged rapamycin release. This research may lead to the development of novel RGC protection agents and drug delivery techniques, as well as the creation of multifunctional COF-based biomaterials for glaucoma retinopathy.

Keyphrases

drug delivery
mouse model
induced apoptosis
cancer therapy
optic nerve
liver failure
cell cycle arrest
drug induced
respiratory failure
drug release
signaling pathway
adverse drug