Differential Associations of Mobility With Fronto-Striatal Integrity and Lesion Load in Older Adults With and Without Multiple Sclerosis.
Mark E WagshulFrederick W FoleyKapil ChaudharyMichael L LiptonRobert W MotlMeltem IzzetogluManuel E HernandezMary Ann PiconeRoee HoltzerPublished in: Neurorehabilitation and neural repair (2023)
Comparing older persons with and without MS, we provide compelling evidence of a double dissociation between the presence of mobility impairment and two neuroimaging markers of white matter integrity, fronto-striatal fractional anisotropy, and whole brain lesion load.