Delivery of microRNA-302a-3p by APTES modified hydroxyapatite nanoparticles to promote osteogenic differentiation in vitro.

Pirawish LimlawanLaurine MargerStéphane DurualAnjalee Vacharaksa

Published in: BDJ open (2023)

HA-NPs-APTES may support the delivery of miRNA-302a-3p into bone cells, as assessed by osteogenic gene expression and differentiation improvement once this combination is used on osteoblast cultures.

Keyphrases

gene expression
mesenchymal stem cells
bone regeneration
bone marrow
induced apoptosis
cell cycle arrest
dna methylation
bone mineral density
oxidative stress
soft tissue
signaling pathway
postmenopausal women
pi k akt