Six months survival and risk factors for attrition for patients detected with cryptococcal antigenemia through screening in Malawi.
Master R O ChisaleAlex JordanPocha S KamudumuliBernard MvulaMichael OdoAlice MaidaJames KanduluBen ChilimaFrank W SinyizaPauline KatunduHsin-Yi LeeRebecca MteghaTsung-Shu Joseph WuJoseph BitirinyoRose NyirendaThoko KaluaGreg GreeneTom ChillerPublished in: PloS one (2023)
Overall, our findings indicate a need for routine access to CrAg screening and pre-emptive fluconazole treatment as a way to detect cryptococcal antigenemia and prevent CM in outpatient and inpatient settings. Rapid access to diagnosis and treatment for cryptococcal meningitis (CM) with gold-standard antifungals is needed to improve survival of patients with advanced HIV in Malawi.
Keyphrases
- end stage renal disease
- ejection fraction
- newly diagnosed
- antiretroviral therapy
- chronic kidney disease
- hiv infected
- hiv positive
- human immunodeficiency virus
- hiv testing
- prognostic factors
- candida albicans
- palliative care
- hepatitis c virus
- men who have sex with men
- clinical practice
- cerebrospinal fluid
- south africa
- quantum dots