New insights into the genetics of mandibular retrognathism: novel candidate genes.

Eva Paddenberg Erika Calvano Küchler Caio Luiz Bittecourt Reis Alice Corrêa Silva-Sousa Christian Kirschneck

Published in: Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie (2024)

SNPs in EGF (rs4444903 and rs2237051) and EGFR (rs2227983) were associated with MR in our German sample and could be genetic biomarkers for early and individualized diagnostic identification of retrognathic mandibular development by means of genetic screening tests.

Keyphrases

genome wide
small cell lung cancer
copy number
epidermal growth factor receptor
dna methylation
tyrosine kinase
magnetic resonance
growth factor
cone beam computed tomography
magnetic resonance imaging
genome wide association