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Associations between Pharmacotherapy for Cardiovascular Diseases and Periodontitis.

Ewa Pająk-ŁysekMaciej PolakGrzegorz KopecMateusz PodolecMoïse DesvarieuxAndrzej PajakJoanna Zarzecka
Published in: International journal of environmental research and public health (2021)
PD was found in 74% of participants. The range of cardioprotective drug use among participants was 7% (ARBs) to 32% (beta-blockers). After adjusting for age, sex, number of teeth, smoking, and education, ASA's use was related to a lower prevalence of PD in all dentate participants (odds ratio (OR) = 0.63, 95% confidence interval (CI): 0.40-0.99). The use of ARBs and statins was found to be associated with a higher prevalence of PD in persons having ≥6 teeth (odds ratio (OR) = 3.57, 95% CI: 1.06-11.99 and OR = 1.81, 95% CI: 1.03-3.16, respectively). Further adjustment for CVD risk factors, history of coronary heart disease, and other chronic diseases did not attenuate the results. There was no significant relation between PD and the use of other cardioprotective drugs.
Keyphrases
  • risk factors
  • cardiovascular disease
  • healthcare
  • smoking cessation
  • drug induced
  • coronary artery disease
  • adverse drug