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Full-Length Immune Repertoire Reconstruction and Profiling at the Transcriptome Level Using Long-Read Sequencing.

Xuanmei LuoLili ZhangYifei LiChang LiGaoyuan SunChunli ZhangYu FuHaozhen LvMing LiuHongyuan CuiDali CaiLihui ZouJie MaFei Xiao
Published in: Clinical chemistry (2024)
FLIRseq enables unbiased and comprehensive analyses of direct V(D)J recombination and immunoglobulin classes, thereby contributing to characterizing pathogenic mechanisms, monitoring minimal residual disease, and customizing adoptive cell therapy.
Keyphrases
  • cell therapy
  • single cell
  • rna seq
  • stem cells
  • mesenchymal stem cells
  • dna repair
  • dna damage
  • single molecule
  • high throughput sequencing
  • gene expression
  • genome wide
  • bone marrow