Association of GLP1R Polymorphisms With the Incretin Response.

Edgar Gerardo Dorsey-TreviñoVarinderpal KaurJosep Maria Mercader Jose C FlorezAaron Leong

Published in: The Journal of clinical endocrinology and metabolism (2022)

GLP1R variation is associated with differences in GLP-1 levels following an OGTT load despite no differences in insulin levels, highlighting altered incretin signaling as a potential mechanism by which GLP1R variation affects T2D risk.

Keyphrases

type diabetes
risk assessment
adipose tissue
human health
climate change
weight loss
insulin resistance