The effect of pH on thrombin generation-An unrecognized potential source of variation.
Søren Risom KristensenJette NyboShona PedersenPublished in: Research and practice in thrombosis and haemostasis (2020)
Modifications of plasma pH can significantly alter thrombin generation. In alkaline samples, for example, after lengthy storage in a freezer where pH can increase considerably, thrombin generation is lowered. To minimize this effect, plasma should be stored in tubes filled to the maximum volume.
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