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Three-Component Tandem Amidosulfenylation of Alkenes for the Synthesis of β-Succinimide Sulfides.

Lin YaoWenjian LiFuhong XiaoXiao-Lan Chen
Published in: The Journal of organic chemistry (2023)
An environmentally benign multicomponent strategy for the amidosulfenylation of alkenes for the synthesis of β-succinimide sulfides is disclosed. In this process, common disulfides smoothly act as a sulfur-based source, and N -iodosuccinimide (NIS) is used not only as a free radical initiator but also as an N -nucleophile. A broad range of functional groups are tolerated in this reaction system.
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