Resveratrol analogues present effective antileishmanial activity against promastigotes and amastigotes from distinct Leishmania species by multitarget action in the parasites.

Luciana Maria Ribeiro AntinarelliRaissa Soares MeinelEduardo Antonio Ferraz CoelhoAdilson David da SilvaElaine Soares Coimbra

Published in: The Journal of pharmacy and pharmacology (2019)

Data indicate that the antileishmanial activity of AR26 is related to multitarget action, and the resveratrol analogues could be used in future studies as antileishmanial agent.

Keyphrases

molecular docking
electronic health record
big data
structure activity relationship
current status
artificial intelligence
plasmodium falciparum
molecular dynamics simulations
data analysis