Malaria Transmission Intensity Likely Modifies RTS, S/AS01 Efficacy Due to a Rebound Effect in Ghana, Malawi, and Gabon.
Griffin J BellVarun GoelPaulin EssoneDavid DosooBright AduBenedicta Ayiedu MensahStephaney GyaaseKenneth WiruFabrice MougeniMusah OseiPamela MinsokoCyrus SinaiKaramoko NiaréJonathan J JulianoMichael HudgensAnita GhansahPortia KamthunziTisungane MvaloSelidji Todagbe AgnandjiJeffrey A BaileyKwaku Poku AsanteMichael EmchPublished in: The Journal of infectious diseases (2022)
These findings suggest that interventions, including the fourth RTS,S dose, that protect vaccinated individuals during the potential rebound period should be implemented for high-transmission settings.