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Intravenous thrombolysis before endovascular therapy for large vessel strokes can lead to significantly higher hospital costs without improving outcomes.

Ansaar T RaiSoHyun BooChelsea BusemanAmelia K AdcockAbdul R TarabishyMaurice M MillerThomas D RobertsJennifer R DomicoJeffrey S Carpenter
Published in: Journal of neurointerventional surgery (2017)
IV rt-PA did not improve recanalization, thrombectomy efficacy, functional outcomes, or length of stay. Combined therapy was associated with significantly higher total and direct hospital costs than endovascular therapy alone.
Keyphrases
  • healthcare
  • acute ischemic stroke
  • pulmonary embolism
  • acute care
  • adverse drug
  • high dose
  • middle cerebral artery
  • aortic dissection
  • bone marrow
  • weight loss
  • smoking cessation
  • glycemic control