Calcium Sensing Receptor Variants Increase Pulmonary Hypertension Susceptibility.

Bingxun LiuYun-Peng WeiXiaohang FanXiaoyi HuZeshuai ChenXiaoyuan LiuYan XuLu WangTao WangMatthieu RuizJocelyn DupuisPing YuanJinming LiuSongling HuangLiping ZhuZhi-Cheng Jing Qinghua Hu

Published in: Hypertension (Dallas, Tex. : 1979) (2022)

minor alleles of rs1042636, rs6776158, rs1048213, and rs9883099 contribute to the development and severity of IPAH. These findings may benefit clinical prognosis and treatment for IPAH.

Keyphrases

pulmonary hypertension
copy number
gene expression
pulmonary arterial hypertension
genome wide
replacement therapy