Linking epigenetic signature and metabolic phenotype in IDH mutant and IDH wildtype diffuse glioma.
Yannick BraunKatharina FilipskiSimon BernatzPeter BaumgartenBastian RollerJenny ZinkePia S ZeinerElena IlinaChristian SenftMichael W RonellenfitschKarl H PlateOliver BährElke HattingenJoachim P SteinbachMichel MittelbronnPatrick N HarterPublished in: Neuropathology and applied neurobiology (2020)
A mitochondrial signature was associated with increased survival in all analyses, which could indicate tumour subgroups with specific metabolic vulnerabilities.