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Impaired adaptive immune response in COVID-19 convalescent patients with hematological malignancies.

Elżbieta KalicińskaDonata SzymczakIga AndrasiakAneta MilanowskaAleksandra KiragaAlan MajeranowskiPaula JabłonowskaJustyna RybkaZaucha MaciejTomasz Wrobel
Published in: European journal of haematology (2022)
Our findings showed a profound impairment of the adaptive immune response in hematological convalescents which might be a result of persistent activation of T cells. Convalescents with lymphoid malignancies showed more pronounced depletion of key T lymphocytes subpopulations in creating an effective adaptive response and immune memory.
Keyphrases
  • immune response
  • coronavirus disease
  • sars cov
  • dendritic cells
  • toll like receptor