Multimodality Approach to the Diagnosis and Assessment of Uveitic Macular Edema.
Sana KhochtaliCarl P HerbortChristine FardeauFederico MaestriMoncef KhairallahPublished in: Ocular immunology and inflammation (2020)
Purpose: To provide an overview of the role of multimodality approach to the diagnosis and assessment of uveitic macular edema (UME). Methods: Review of literature. Results: Optical coherence tomography (OCT) has become the gold standard in the detection, quantification, monitoring of treatment, and determination of prognosis in UME. Fluorescein angiography provides essential information on blood-retinal barrier disruption as a result of intraocular inflammation and allows detection of associated retinal ischemia and neovascularization. Dye-less OCT angiography can reveal the presence of various qualitative and quantitative retinal microvascular changes mostly involving the deep capillary plexus. Reading acuity and retinal sensitivity assessed by microperimetry represent sensitive measures for visual dysfunction in UME and may supplement distance visual acuity in the follow-up of patients with UME. Conclusion: Conventional and new imaging modalities and ancillary tests complement each other in the diagnosis, assessment, and monitoring of patients with UME.
Keyphrases
- optical coherence tomography
- diabetic retinopathy
- optic nerve
- oxidative stress
- high resolution
- systematic review
- healthcare
- real time pcr
- genome wide
- label free
- computed tomography
- gene expression
- dna methylation
- mass spectrometry
- social media
- combination therapy
- cataract surgery
- tandem mass spectrometry
- sensitive detection