Enantioselective formal synthesis of the marine macrolide (-)-callyspongiolide.

Aina Urbina Núria Llor Maria Vittoria Barbieri Joan Bosch Mercedes Amat

Published in: Chemical communications (Cambridge, England) (2021)

A short enantioselective synthesis of the macrocyclic core 19 of callyspongiolide, involving a homocrotylboration of aldehyde 4, a Still-Genari olefination, an esterification with alcohol 17, and a ring-closing metathesis, is reported.

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