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White matter hyperintensity volume in pre-diabetes, diabetes and normoglycemia.

Sergio GrosuRoberto LorbeerFelix HartmannSusanne RospleszczFabian BambergChristopher L SchlettFranziska GalieSonja SelderSigrid AuweterMargit HeierWolfgang RathmannKatharina Mueller-PeltzerKarl-Heinz LadwigAnnette PetersBirgit B Ertl-WagnerSophia Stoecklein
Published in: BMJ open diabetes research & care (2021)
Our results indicate that high 2-hour serum glucose concentration in OGTT, but not fasting glucose levels, may be an independent risk factor for the development of WMHs, with the potential to inform intensified prevention strategies in individuals at risk of WMH-associated morbidity.
Keyphrases
  • blood glucose
  • glycemic control
  • type diabetes
  • white matter
  • cardiovascular disease
  • blood pressure
  • insulin resistance
  • multiple sclerosis
  • adipose tissue