Age-Stratified Risk of Cerebral Venous Sinus Thrombosis After SARS-CoV-2 Vaccination.

Katarzyna KrzywickaAnita van de MunckhofMayte Sánchez van KammenMirjam R HeldnerKatarina JoodErik LindgrenTurgut TatlisumakJukka PutaalaJohanna A Kremer HovingaSaskia MiddeldorpMarcel M LeviCharlotte CordonnierMarcel ArnoldAeilko H ZwindermanJosé M FerroJonathan M CoutinhoDiana Aguiar de Sousa

Published in: Neurology (2021)

The risk of CVST with thrombocytopenia within 28 days of first-dose vaccination with ChAdOx1 nCov-19 was higher in younger age groups. The risk of CVST with thrombocytopenia was slightly increased in patients receiving Ad26.COV2.S compared with the estimated background risk. The risk of CVST with thrombocytopenia was not increased in recipients of SARS-CoV-2 mRNA vaccines.

Keyphrases

sars cov
respiratory syndrome coronavirus
pulmonary embolism
subarachnoid hemorrhage
binding protein
brain injury
blood brain barrier