Cancer-induced Cardiac Atrophy Adversely Affects Myocardial Redox State and Mitochondrial Oxidative Characteristics.
David E LeeJacob L BrownMegan E Rosa-CaldwellRichard A PerryLemuel A BrownWesley S HaynieTyrone A WashingtonMichael P WiggsNarasimhan RajaramNicholas P GreenePublished in: JCSM rapid communications (2020)
These results substantiate metabolic cardiotoxic effects attributable to tumor-associated factors and provide insight into interactions between mitochondrial mRNA translation, ROS mitigation, oxidative capacity and hypoxia resistance.