Epithelial-mesenchymal transition and microRNAs: Challenges and future perspectives in oral cancer.

Cátia Sofia da Costa DominguesBeatriz Prazeres SerambequeMafalda Sofia Laranjo CândidoCarlos Miguel Machado MartoFrancisco José de Baptista VeigaAna Bela Sarmento Antunes Cruz RibeiroAna Rita Ramalho FigueirasMaria Filomena Roque BotelhoMarília de Assunção Rodrigues Ferreira Dourado

Published in: Head & neck (2018)

Therefore, we propose that targeting therapies to epithelial-mesenchymal transition-type cells, namely, coordinating microRNAs and/or hydrophobic drugs, such as conventional therapy, could be a promising strategy to improve the outcomes of patients with OSCC.

Keyphrases

epithelial mesenchymal transition
induced apoptosis
transforming growth factor
signaling pathway
cell cycle arrest
cancer therapy
ionic liquid
endoplasmic reticulum stress
oxidative stress
pi k akt
mesenchymal stem cells
adipose tissue
bone marrow
drug delivery
drug induced
glycemic control