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Conjugation of VEGFR1/R2-targeting peptide with gold nanoparticles to enhance antiangiogenic and antitumoral activity.

Pegah ZanjanchiS Mohsen AsghariHassan MohabatkarMostafa ShourianMehdi Shafiee Ardestani
Published in: Journal of nanobiotechnology (2022)
Conjugation to GNPs not only improved the efficacy of VGB3 peptide but also extended the intervals between treatments without adverse effects. These results suggest that GNP-VGB3 is a promising candidate for clinical translation.
Keyphrases
  • gold nanoparticles
  • cancer therapy
  • vascular endothelial growth factor
  • endothelial cells