Lipidomic analysis reveals altered lipid profiles of gingival tissues with periodontitis.

Min ZhouChen LiXue HanBohan YuXiang-Zhen YanYan ZhangXiao-Juan Yang

Published in: Journal of clinical periodontology (2022)

LysoPCs, DGs, and PEs were significantly up-regulated, whereas TGs were down-regulated in gingival tissues of patients with periodontitis. Correspondingly, the immunohistochemical staining of ABHD5/CGI-58, sPLA2, and sPLA2-IIA in gingival tissues was consistent with the downstream production of lipid classes (lysoPCs, TGs, and DGs).

Keyphrases

gene expression
transcription factor