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Impact of a shift in nuchal translucency measurements on the detection rate of first-trimester Down syndrome screening: A population-based study.

Nicolas FriesLaurent J SalomonFrançoise MullerSophie DreuxVéronique Houfflin-DebargePhilippe CoquelPascale KleinfingerMarc Dommerguesnull null
Published in: Prenatal diagnosis (2018)
In France, following a policy of quality assessment without standardized credentialing, the distribution of NT measurements did not fit the expected distribution. Down syndrome detection rate was 10% lower in screenings by sonographers with a median NT < 0.80 MoM.
Keyphrases
  • loop mediated isothermal amplification
  • real time pcr
  • label free
  • healthcare
  • public health
  • sensitive detection