Calcium hydroxide-loaded PLGA biodegradable nanoparticles as an intracanal medicament.

Firas ElmsmariJosé Antonio González SánchezFernando Duran-SindreuRoumaissa BelkadiMarta EspinaMaria Luisa GarcíaElena Sánchez-López

Published in: International endodontic journal (2021)

Ca(OH)₂-loaded PLGA NPs were successfully optimized and characterized. The NPs exhibited a prolonged drug release profile and superior penetration inside dentinal tubules of extracted teeth when compared to Ca(OH)2 .

Keyphrases

drug delivery
drug release
cancer therapy
protein kinase
oxide nanoparticles