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Analytical and clinical performances of the automated Lumipulse cerebrospinal fluid Aβ42 and T-Tau assays for Alzheimer's disease diagnosis.

Jean-Louis BayartBernard J HanseeuwAdrian IvanoiuVincent van Pesch
Published in: Journal of neurology (2019)
Our results demonstrate that the Lumipulse Aβ1-42 and T-Tau assays show good analytical and clinical performances in the context of patient evaluation referred to a memory clinic. Automated analyzers should be preferred for the measurement of CSF AD biomarkers to reduce inter- and intra-laboratory variability.
Keyphrases
  • cerebrospinal fluid
  • high throughput
  • deep learning
  • primary care
  • liquid chromatography
  • working memory
  • case report
  • cognitive decline
  • mass spectrometry
  • single cell