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Repurposing of respiratory drug theophylline against Candida albicans: mechanistic insights unveil alterations in membrane properties and metabolic fitness.

S SinghZeeshan FatimaK AhmadSaif Hameed
Published in: Journal of applied microbiology (2020)
This study unveils the antifungal potential of THP, a known respiratory drug that can be further utilized for a wider range of applications such as combating fungal infections. The effect of THP with the known antifungal drugs can be exploited in the combinatorial drug approach for treating candidiasis.
Keyphrases
  • candida albicans
  • biofilm formation
  • drug induced
  • adverse drug
  • body composition
  • escherichia coli
  • pseudomonas aeruginosa
  • respiratory tract
  • staphylococcus aureus
  • climate change
  • human health
  • drug discovery