β-Caryophyllene Ameliorates Cyclophosphamide Induced Cardiac Injury: The Association of TLR4/NFκB and Nrf2/HO1/NQO1 Pathways.

Published in: Journal of cardiovascular development and disease (2022)

BCP administration was associated with activated Nrf2/HO1/NQO1 and inhibited TLR4/NFκB pathways with subsequent enhanced anti-oxidative capacity and diminished inflammatory and apoptosis responses.

Keyphrases

oxidative stress
diabetic rats
pi k akt
toll like receptor
inflammatory response
nuclear factor
cell cycle arrest
signaling pathway
lps induced
immune response
high glucose
low dose
high dose
left ventricular
mouse model
cell proliferation
endothelial cells
drug induced
atrial fibrillation